Buy Levitra Online

Levitra overview

Levitra also called Vardenafil, is mainly used to manage Erectile Dysfunction. This medication is a similar ED treatment to avanafil (Spedra), Sildenafil (Viagra), and tadalafil. Levitra’s molecular structure varies from Sildenafil/Viagra, which in turn offers it with a longer duration of action.

This medication is also helpful for patients with diabetes. Levitra can be often used as a treatment for premature ejaculation. You may buy Levitra online as it is a relatively safe and effective medication.

Levitra’s Mode of Action

Release of Nitric Oxide- Endothelial cells and nerve endings release NO in the corpus cavernosum during sexual stimulation.

Production to cGMP- The nitric oxide then helps to activate an enzyme known as guanylate cyclase which leads to higher cGMP synthesis in the soft muscle cells presented in the corpus cavernosum.

Smooth blood flow and muscle relaxation- The cGMP helps to share messages and triggers the relaxation of the soft muscles present in the penile blood vessels and the nearby erectile tissue. Due to this relaxation, blood vessels easily dilate and enhance blood flow into the penis which result in an erection.

Inhibition of PDE5- The cGMP concentration is generally controlled by its rate of degradation and synthesis by numerous enzymes (PDE5). PDE5 is the most abundant enzyme in the cavernosum of the corpus that turns cGMP into an inactive form (5-GMP).

Prolonged impact- Vardenafil blocks the PDE5 enzyme selectively and also blocks the rapid degradation of cGMP. It helps to maintain increased numbers of cGMP in the penile tissue, which prolongs the soft relaxation of muscle and the higher blood flow, thereby increasing the erectile reaction to sexual stimulation.

Active and inactive ingredients of Levitra

Active ingredient- Vardenafil (as vardenafil hydrochloride)

Inactive ingredients

• Crospovidone
• Microcrystalline cellulose
• Magnesium stearate
• Anhydrous colloidal silica (colloidal silicon dioxide)
• Polyethylene glycol
• Hypromellose
• Yellow ferric oxide (CI 77492)
• Red ferric oxide (CI 77491)
• Titanium dioxide

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FDA Status and history of Levitra

Primary Approval (August 19, 2003)- Levitra (vardenafil) got primary approval from FDA, manufactured by Bayer Corporation, to manage ED (erectile dysfunction).

Safety Labeling adjustments (Ongoing- Following its approval, the FDA imposed many labeling adjustments for Levitra and other comparable medications (PDE5 inhibitors) based on post-marketing reports of infrequent, but serious, side effects.

• Sudden Hearing Loss- In October 2007, the FDA mandated manufacturers to add conspicuous warnings regarding the potential risk of sudden hearing loss.

• Vision Loss (NAION)- The risk of non-arteritic ischemic optic neuropathy (NAION), a type of abrupt vision loss, was also included in the labeling.

FDA determination (2019 and 2023)- The food and drug administration officially monitored the withdrawal and analyzed that the pills of Levitra were indeed not removed for effectiveness or safety concerns. This determination enabled for the continued approval of vardenafil generic products.

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Dosage guidelines of Levitra

Primary dosage- Primarily most adults started with 10 mg.

Timing- Almost an hour before participating in sexual activity, effects may stay for more than 4 hours.

Frequency- Once daily maximum. 

Adjustment- The dosage of Levitra might be adjusted between 5 mg and 20 mg based on tolerability and response.

Food- Can be used with or without having meals, though high-fat meals may late onset.

Sexual stimulation- Essential for the drug to show the effects.

Dosage might require changes or the drug might be contraindicated based on health conditions or other drugs-

Group/condition of patient	Dosage Guideline
Elderly 65 years	Initial dosage started with 5 mg
Child-Pugh B (Modest Hepatic Impairment)	Begin with 5 mg, and not be allowed to exceed 10 mg. Not required for severe impairment.
Renal Impairment	No need for modification for mild to acute cases; not required for dialysis patients.
Using Alpha-Blockers	Begin with 5 mg after stable on the therapy of alpha-blocker
Using potent inhibitors of CYP3A4	Dosages must be avoided or reduced.

These instructions are based on general dosing guides. While buying Levitra online, always consult an experienced healthcare expert for personalized dosing guide and safety related information.

Warnings and precautions related to Levitra

Guanylate Cyclase and Nitrates Stimulators- Avoid taking Levitra if you are using any type of organic nitrates for managing heart issues or chest discomfort, or guanylate cyclase stimulators such as Adempas or riociguat. Combining them might be the reason for severe and sudden possibly fatal reduction in BP.

Cardiovascular health- The chance of cardiac arrest can be posed with sexual activity. People with pre-existing heart issues such as current heart attack, unstable angina, or stroke, low or high uncontrolled BP, severe heart failure should not consume this medication.

Sudden vision loss- If you notice sudden loss of vision in one or both eyes, you should stop using this medication and seek urgent medical help. It might be the symptoms of NAION, a condition that may cause permanent blindness.

People with diabetes, high cholesterol, high BP, and over 50 years old must avoid taking Levitra.

Sudden loss of hearing- You should not take this medication and inform your healthcare expert immediately if you notice a sudden reduction or are not able to hear. Sometimes it may happen with tinnitus (ringing in the ears) or dizziness.

Allergic reactions- Seek urgent medical attention if you have symptoms of an allergic reaction such as difficulty breathing, hives, or swelling of the body parts.

Grapefruit and alcohol- You should avoid intaking higher quantities of alcoholic beverages as it may enhance the chance of adverse reactions like dizziness and low BP. The same way, you should avoid consuming grapes while using this drug, as it may raise drug levels in the body.

If you are planning to buy Levitra online, following these details may help you to achieve the best desired outcomes from the medication.

Pills appearance of Levitra

Strength	Imprint	Color	Shape	NDC.
20 mg	BAYER BAYER 20	Orange	Round	00085-1934
10 mg	BAYER BAYER 10	Orange	Round	00026-8730
5 mg	BAYER BAYER 5	Orange	Round	00026-8720

Before buying Levitra online, ensure with these identification details that you are getting the genuine medication.

Levitra undesired effects

Stop taking Levitra and get urgent medical attention if you have-

• Sudden vision loss or vision changes
• Symptoms of heart attack- Chest pressure or pain, spreaded pain inside your shoulder or jaw, sweating, or nausea
• Sudden vision loss or vision changes
• Erection is unbearable or stays more than 4 hours

Levitra might cause severe adverse reactions. Stop taking this medication and contact your healthcare expert immediately if you have-

• Shortness of breath
• Lightheadedness
• Seizure, irregular heartbeat

Common side effects-

• Dizziness, headache
• Back pain, upset stomach
• Sinus pain, flushing

Less common side effects-

• Chest heaviness or tightness
• Blurred vision, blindness
• Cold sweats, chills
• Eye pain, faintness

Many of these side effects may disappear as your body gets used to the medication. You must be cautious after you buy Levitra online.

Best place to order Levitra online

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FAQs (Frequently Asked Questions)

Who should avoid taking Levitra?

Those who use nitrate containing drugs should avoid taking Levitra. The combination of this medication with nitrates may cause reduction in BP, dizziness, or even death.

How much time does Levitra stay?

This medication has an eight hour duration of action. Among older individuals and those with renal or liver illness, the time it takes to remove Levitra might be higher, which means the medication functions for a longer duration.

Is combining this medication and alcohol dangerous?

Research shows that combining alcohol and Levitra results in no major side effects. However, because alcohol lowers BP, it may impair Levitra’s erection-inducing impact.

How to take Levitra?

You should take this medication the same as instructed by your healthcare expert or as directed on the medication label. Avoid taking in higher amounts of the indicated dosage or more than the required period.